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Scientists analyzed research that examined how titanium dioxide nanoparticles interact with the brain for a 2015 review published in Nanoscale Research Letters. The researchers wrote: “Once the TiO2 NPs are translocated into the central nervous system through [certain] pathways, they may accumulate in the brain regions. For their slow elimination rates, those NPs could remain in the brain zones for a long period, and the Ti contents would gradually increase with repeated exposure.” After reviewing dozens of studies, the scientists concluded: “Long-term or chronic exposure to TiO2 nanoparticles could potentially lead to the gradually increased Ti contents in the brain, which may eventually induce impairments on the neurons and glial cells and lead to CNS dysfunction as a consequence.”

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The photocatalytic properties of titanium dioxide are particularly interesting. When exposed to ultraviolet radiation, TiO2 can catalyze reactions that decompose organic compounds, leading to its use in self-cleaning surfaces and air purification systems When exposed to ultraviolet radiation, TiO2 can catalyze reactions that decompose organic compounds, leading to its use in self-cleaning surfaces and air purification systems When exposed to ultraviolet radiation, TiO2 can catalyze reactions that decompose organic compounds, leading to its use in self-cleaning surfaces and air purification systems When exposed to ultraviolet radiation, TiO2 can catalyze reactions that decompose organic compounds, leading to its use in self-cleaning surfaces and air purification systemschemical titanium dioxide. This property is utilized in construction materials like concrete and glass, where the titanium dioxide helps to break down pollutants and reduce maintenance requirements.

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There are numerous manufacturers of titanium dioxide; the largest include Delaware-based Chemours (a spin-off of DuPont Chemical), Texas-based Kronos, and China-based Lomon Billions Group, all of which manufacture pigments for use in products like paints, coatings, and plastics. UK-based Venator is a major supplier of titanium dioxide used in food and cosmetics, along with paints, paper, plastic, and more. As a pigment, it is called Pigment White 6 (PW6), titanium white, or CI 77891. As a food additive, it is known as E171.

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